WebThe encoded cytoplasmic protein plays a role in multiple processes including cell signaling and lipid metabolism by facilitating the transfer of phosphatidylinositol between membrane compartments. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on ... Phosphatidylinositol transfer protein (PITP) or priming in exocytosis protein 3 (PEP3) is a ubiquitous cytosolic domain involved in transport of phospholipids from their site of synthesis in the endoplasmic reticulum and Golgi to other cell membranes. See more PITP has been also shown to be an essential component of the polyphosphoinositide synthesis machinery and is hence required for proper signalling by epidermal growth factor and f-Met-Leu-Phe, as well as for See more Along with the structurally unrelated Sec14p family (found in Pfam PF00650), this family can bind/exchange one molecule of phosphatidylinositol (PI) or phosphatidylcholine … See more The family of human phosphatidylinositol transfer proteins has several members: • Phosphatidylinositol transfer protein, alpha (PITPNA) • Phosphatidylinositol transfer protein, beta (PITPNB) • Phosphatidylinositol transfer protein, cytoplasmic 1 See more
UniProt
WebAug 5, 2024 · A protein that helps move lipids within cells — phosphatidylinositol transfer protein — seems to be a key regulator in the migration of cortical neurons during development and may play a role in neurodevelopmental conditions. ... An artificial-intelligence tool from the company Deep Mind has predicted the shape of 200 million … WebAbstract The plant patellin (PATL) proteins are yeast Sec14 protein (Sec14p)-like phosphatidylinositol transfer proteins (PITPs), which are widely distributed across the plant kingdom. The model plant Arabidopsis has six PATL members (designated as … great house hawkhurst
The PITP family of phosphatidylinositol transfer proteins Genome
WebPhosphatidylinositol transfer proteins (PITPs) 3 are conserved proteins that participate in many cellular processes including cell signaling, membrane traffic, and lipid metabolism ( … WebEukaryotic phosphatidylinositol transfer protein is a ubiquitous multifunctional protein that transports phospholipids between membrane surfaces and participates in cellular phospholipid metabolism during signal transduction and vesicular trafficking. The three-dimensional structure of the α-isoform of rat phosphatidylinositol transfer protein … WebJan 1, 2010 · Phosphatidylinositol transfer protein (PITP) or priming in exocytosis protein 3 (PEP3) is a ubiquitous cytosolic domain involved in transport of phospholipids from their … great house grand cayman